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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STAT5A
All Species:
22.73
Human Site:
Y665
Identified Species:
50
UniProt:
P42229
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42229
NP_003143.2
794
90647
Y665
D
R
L
G
D
L
S
Y
L
I
Y
V
F
P
D
Chimpanzee
Pan troglodytes
XP_001165762
794
90647
Y665
D
R
L
G
D
L
S
Y
L
I
Y
V
F
P
D
Rhesus Macaque
Macaca mulatta
XP_001109557
794
90645
Y665
D
R
L
G
D
L
S
Y
L
I
Y
V
F
P
D
Dog
Lupus familis
XP_548091
794
90625
Y665
D
R
L
G
D
L
N
Y
L
I
Y
V
F
P
D
Cat
Felis silvestris
Mouse
Mus musculus
P42230
793
90813
Y665
D
R
L
G
D
L
N
Y
L
I
Y
V
F
P
D
Rat
Rattus norvegicus
Q62771
793
90815
Y665
D
R
L
G
D
L
N
Y
L
I
Y
V
F
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6DV79
771
88152
I585
A
L
W
N
E
G
Y
I
M
G
F
I
S
K
E
Frog
Xenopus laevis
Q7ZXK3
766
87581
I585
A
L
W
N
E
G
Y
I
I
G
F
I
S
K
E
Zebra Danio
Brachydanio rerio
NP_919368
785
89465
M643
P
N
K
A
G
E
R
M
V
W
N
L
T
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24151
761
86396
L631
L
R
F
S
D
S
E
L
G
G
V
T
I
A
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NAD6
706
80563
C549
L
A
S
R
I
A
S
C
P
Q
L
K
D
I
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
96.8
N.A.
96.3
95.8
N.A.
N.A.
28.9
28.9
77.4
N.A.
31.3
N.A.
24.6
N.A.
Protein Similarity:
100
100
98.9
98.6
N.A.
98.1
97.8
N.A.
N.A.
48.3
49.2
87.4
N.A.
48.1
N.A.
43.5
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
0
0
6.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
33.3
33.3
20
N.A.
13.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
10
0
10
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
55
0
0
0
64
0
0
0
0
0
0
0
10
0
55
% D
% Glu:
0
0
0
0
19
10
10
0
0
0
0
0
0
0
19
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
19
0
55
0
0
% F
% Gly:
0
0
0
55
10
19
0
0
10
28
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
19
10
55
0
19
10
10
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
10
0
19
0
% K
% Leu:
19
19
55
0
0
55
0
10
55
0
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
19
0
0
28
0
0
0
10
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
10
0
0
0
0
64
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
64
0
10
0
0
10
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
10
10
0
10
37
0
0
0
0
0
19
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
10
55
0
0
0
% V
% Trp:
0
0
19
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
19
55
0
0
55
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _